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US Patent 7855274 Recombinant factor VIII having increased specific activity

Patent 7855274 was granted and assigned to University of Rochester on December, 2010 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to recombinant factor VIII having a specific activity that is higher than that of the corresponding wild-type factor VIII. The present invention also relates to methods of making and using the recombinant factor VIII. The present invention also relates to an isolated nucleic acid molecule that encodes the recombinant factor VIII, as well as DNA expression systems and host cells containing the isolated nucleic acid molecule.

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