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US Patent 7858083 Pan cancer oncolytic vectors and methods of use thereof

Patent 7858083 was granted and assigned to BioSante Pharmaceuticals on December, 2010 by the United States Patent and Trademark Office.

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Patent abstract

Replication-competent adenoviral vectors which selectively replicate in cancer cells are provided. The replication-competent viral vectors comprise an E2F responsive promoter and/or a telomerase promoter operatively linked to an adenoviral coding region. The replication-competent adenoviral vectors effectively replicate in a variety of types of cancer cells and find broad utility in the treatment of cancer.

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