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US Patent 7858093 Controlled-release immunogenic formulations to modulate immune response

Patent 7858093 was granted and assigned to Iowa State University on December, 2010 by the United States Patent and Trademark Office.

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Patent abstract

Single-dose controlled-release immunogenic formulations, such as vaccines, based on bioerodible polyanhydride copolymer or homopolymer microparticles for the control of immune response mechanisms are provided. The copolymer or homopolymer microparticles degrade by surface-erosion from in vivo hydrolysis of anhydride linkages at the surface of the microparticle, which results in controlled release of immunogen(s) to a patient.

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