Disclosed is an apparatus and method for operating a microwave amplifier with improved efficiency and reduced harmonic emissions. The disclosed amplifier includes a variable rail voltage supply and a variable input drive stage. A controller continually monitors the amplifier output and adjusts the rail voltage and input drive signal to achieve high efficiency and low harmonic emissions. The amplifier may include a dynamic bias controller configured to operate the gain elements outside the linear region. Efficiencies of over 70% may be achieved by the disclosed amplifier.