Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Min-kyung So0
Hequan Yao0
Jianghong Rao0
Date of Patent
January 11, 2011
0Patent Application Number
120608640
Date Filed
April 1, 2008
0Patent Primary Examiner
Patent abstract
A bioluminogenic assay system including: providing a bioluminogenic substrate incorporating a beta-lactam antibiotic, a bioluminescence initiating compound, and a chemical linkage joining the beta-lactam antibiotic to the bioluminescence initiating compound; exposing the bioluminogenic substrate to a beta-lactamase enzyme that catalyzes the release of the bioluminescence initiating compound from the bioluminogenic substrate; co-exposing the bioluminogenic substrate to a bioluminescence indicator reaction that employs the bioluminescence initiating compound as a substrate; and detecting a light from the bioluminescence indicator reaction as a measure of the activity of the beta-lactamase enzyme.
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