US Patent 7871795 Targeted
Patent 7871795 was granted and assigned to VIRxSYS on January, 2011 by the United States Patent and Trademark Office.
All edits
The present invention provides methods and compositions for generating novel nucleic acid molecules through RNA trans-splicing that target a highly expressed pre-mRNA and contain the coding sequence of a protein or polypeptide of interest. The compositions of the invention include pre-trans-splicing molecules (PTMs) designed to interact with the target precursor messenger RNA molecule (target pre-mRNA) that is abundantly expressed, and mediate a trans-splicing reaction resulting in the generation of novel chimeric RNA molecule (chimeric RNA) capable of encoding a protein or polypeptide of interest. The invention provides for the in vivo production of chimeric RNA molecules that encode and result in the production of a protein or polypeptide of interest.
US Patent 07871795 Targeted US Patent 7871795 Targeted
US Patent 07871795 Targeted
Find more entities like US Patent 7871795 Targeted
