Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kin-Ming Lo0
Gordon D. Webster0
Pascal André Stein0
Suzanne P. McKenzie0
Date of Patent
January 18, 2011
0Patent Application Number
116476610
Date Filed
December 29, 2006
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Modified interleukin-12 (IL-12) p40 polypeptides are disclosed. The modified polypeptides have alterations in the IL-12p40 subunit to eliminate the protease site between positions Lys260 and Arg261. The modified IL-12p40 polypeptides according to the invention have improved stability compared to wild-type mature human IL-12p40 polypeptides.
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