Systems, methodologies, media, and other embodiments associated with making an automated immune response on a computer that may be infected with a malicious software like a virus are described. One exemplary system embodiment includes a behavior logic that faciltates identifying that a computer is exibiting a behavior that indicates that the computer may be infected by a malicious software. The exemplary system embodiment may also include an immune response logic that is configured to facilitate identifying a process and/or program related to the behavior. The immune response logic may be configured to automatically make an immune response with respect to the process and/or program.