An optical probe, for example, a medical endoscope, having a removable lens cell. In an embodiment, the optical probe has an elongated tube with a proximal portion terminating at a proximal end and a distal portion opposite the proximal portion terminating at a distal end. The elongated tube defines an axial lumen wherein a lens cell holder is disposed proximal the distal portion. The lens cell holder has an axial holder bore for at least partially containing the lens cell within and removably coupled with the holder bore.