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US Patent 7879992 Modification of MyD88 splicing using modified oligonucleotides

Patent 7879992 was granted and assigned to Ionis Pharmaceuticals on February, 2011 by the United States Patent and Trademark Office.

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Patent abstract

Antisense compounds, compositions and methods are provided for modulating the expression of MyD88. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding MyD88. Methods of using these compounds for modulation of MyD88 expression and for treatment of diseases associated with expression of MyD88 are provided.

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