Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Won Jeong Kim0
Jae Chul Lee0
Kwee-Hyun Suh0
Tae Hee Ha0
Chang Hee Park0
Han Kyong Kim0
Hee Sook Oh0
Date of Patent
February 15, 2011
Patent Application Number
11996657
Date Filed
July 11, 2006
Patent Primary Examiner
Patent abstract
Optically pure esomeprazole and its salt can be simply prepared by dissolving (S)-(−)-binol, a weak base and the racemic form of omeprazole in a mixture of a water-compatible organic solvent and water at a high temperature, cooling the mixed solution to crystallize the inclusion complex of esomeprazole and (S)-(−)-binol, and removing the (S)-(−)-binol moiety from the crystallized inclusion complex.
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