Patent 7892546 was granted and assigned to Eli Lilly and Company on February, 2011 by the United States Patent and Trademark Office.
The present invention provides antibodies that bind human CXCR4 and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful in the treatment of tumorigenesis, including tumor growth, invasion, angiogenesis, or metastasis.