US Patent 7892578 Treatment of hematologic disorders
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Patent abstract
The inventors have discovered that hematologic disorders, e.g., both neoplastic (hematologic cancers) and non-neoplastic conditions, can be treated by the induction of mixed chimerism using myeloreductive, but not myeloablative, conditioning. Methods of the invention reduce GVHD, especially GVHD associated with mismatched allogeneic or xenogeneic donor tissue, yet provide, for example, significant graft-versus-leukemia (GVL) effect and the like.
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Patent Inventor Names
Megan Sykes0
Thomas R. Spitzer0
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US Patent 07892578 Treatment of hematologic disorders US Patent 7892578 Treatment of hematologic disorders
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Patent Number
078925780
Patent Number
78925780
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Patent Jurisdiction
Patent Number
078925780
Date of Patent
February 22, 2011
0Patent Application Number
121854270
Date Filed
August 4, 2008
0Official Website
Patent Primary Examiner
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US Patent 07892578 Treatment of hematologic disorders
Infobox
Is a
Patent jurisdiction
Patent number
07892578
Date of patent
February 22, 2011
Patent application number
12185427
Date Filed
August 4, 2008
Patent primary examiner
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