Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Debra Ellies0
Robb Krumlauf0
Date of Patent
February 22, 2011
Patent Application Number
11508701
Date Filed
August 23, 2006
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention is directed to isolated polypeptides and antibodies suitable for producing therapeutic preparations, methods, and kits relating to bone deposition. One objective of the present invention is to provide compositions that improve bone deposition. Yet another objective of the present invention is to provide methods and compositions to be utilized in diagnosing bone dysregulation. The therapeutic compositions and methods of the present invention are related to the regulation of Wise, Sost, and closely related sequences. In particular, the nucleic acid sequences and polypeptides include Wise and Sost as well as a family of molecules that express a cysteine knot polypeptide.
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