Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Barrie Wilkinson0
Rose Mary Sheridan0
Mingqiang Zhang0
Date of Patent
March 1, 2011
0Patent Application Number
122739170
Date Filed
November 19, 2008
0Patent Primary Examiner
Patent abstract
The present invention relates to novel 39-desmethoxy-39-methylrapamycin derivatives, methods for their production, and uses thereof. In a further aspect the present invention provides for the use of these 39-desmethoxy-39 -methylrapamycin derivatives in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.
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