Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Makoto Sakaguchi0
Yusuke Tsukada0
Hiroyuki Tsujimoto0
Date of Patent
March 1, 2011
Patent Application Number
11812459
Date Filed
June 19, 2007
Patent Primary Examiner
Patent abstract
A pharmaceutical preparation comprises nano-level particles (nanospheres) of a biocompatible polymer having, as held on their surfaces, an NFκB decoy capable of binding to NFκB to inhibit its activity. With penetration of the nanoparticles inside cells, the NFκB decoy may be delivered to an affected site and the NFκB decoy may be released from the surfaces of the nanoparticles and may be thereby efficiently and specifically introduced into the affected site.
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