Patent 7901667 was granted and assigned to Mallinckrodt (company) on March, 2011 by the United States Patent and Trademark Office.
The present invention relates to compounds having the general formula: Y-L-BFR-X wherein BFR is a bridged fused ring system; Y is a targeting group; L is optionally present and is a linker for coupling Y to BFR; and X is halogen (e.g., radiohalogen) or a functional group for labelling.