Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Valeria Marigo0
Andrew P. McMahon0
Clifford Tabin0
Philip W. Ingham0
Date of Patent
March 8, 2011
0Patent Application Number
111977210
Date Filed
August 3, 2005
0Patent Primary Examiner
Patent abstract
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
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