Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Robert S. Munson, Jr.0
Lauren O. Bakaletz0
Date of Patent
March 8, 2011
0Patent Application Number
127610740
Date Filed
April 15, 2010
0Patent Primary Examiner
Patent abstract
The invention relates to a mutation within the sap operon of an avirulent clone of a nontypeable strain of Haemophilus influenzae (NTHi). The invention also relates to the NTHi sap operon genes and the polypeptides encoded by these polynucleotide sequences. The invention also relates to a novel 110 kDa NTHi outer membrane protein and the polynucleotide that encodes this outer membrane protein. Methods of screening for NTHi infection, and treating and preventing NTHi related disorders are also contemplated.
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