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US Patent 7902351 Inhibition of viral gene expression using small interfering RNA

Patent 7902351 was granted and assigned to Somagenics, Inc. on March, 2011 by the United States Patent and Trademark Office.

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Current Assignee
Somagenics, Inc.
Somagenics, Inc.
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7902351
Date of Patent
March 8, 2011
Patent Application Number
11444901
Date Filed
June 1, 2006
Patent Primary Examiner
‌
Brian Whiteman
Patent abstract

The invention provides methods, compositions, and kits comprising small interfering RNA (shRNA or siRNA) that are useful for inhibition of viral-mediated gene expression. Small interfering RNAs as described herein can be used in methods of treatment of HCV infection. ShRNA and siRNA constructs targetING the internal ribosome entry site (IRES) sequence of HCV are described.

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