Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Syed Ali0
Jean-Marc Lapierre0
Manish Tandon0
Mark A. Ashwell0
Chiang J. Li0
David Vensel0
Date of Patent
March 8, 2011
0Patent Application Number
118949000
Date Filed
August 21, 2007
0Patent Primary Examiner
Patent abstract
The present invention provides novel tricyclic spiro-oxathiine naphthoquinone derivatives, a synthetic method for making the derivatives, and the use of the derivatives to induce cell death and/or to inhibit proliferation of cancer or precancerous cells. The naphthoquinone derivatives of the present invention are related to the compound known as β-lapachone (3,4-dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione).
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