Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Radim Osicka0
Jirina Loucka0
Mohammed El-Azami El-Idrissi0
Peter Sebo0
Claude Leclerc0
Cécile Bauche0
Daniel Ladant0
Date of Patent
March 15, 2011
0Patent Application Number
117137080
Date Filed
March 5, 2007
0Patent Primary Examiner
Patent abstract
The invention relates to modified Bordetella adenylate cyclase toxins which are deficient for CD11b/CD18 binding and to their use in the preparation of pharmaceutical composition for the treatment of whooping cough and/or for the protection against Bordetella infection. The invention also relates to specific fragments of Bordetella adenylate cyclase comprising the CD11b/CD18 interaction domain and their use, especially for targeting a molecule of interest to CD11b expressing cells.
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