Methods and systems for performing direct memory access (DMA) transfers are described. An invalidate queue (or other storage device) contains an entry associated with a DMA transfer in progress. If the invalidate queue detects an invalidation of a memory page associated with that entry, then it is marked invalid. If the entry is marked invalid during the DMA transfer, then that DMA transfer is aborted. This enables, among other things, DMA transfers to unpinned virtual memory.