A folding knife has a handle, a blade, a locking rod and an unlocking lever. The handle has a dorsal portion. The blade is pivotally mounted and selectively folded in the handle and has a notch. The notch is formed on a spine of the blade. The locking rod is mounted on the dorsal portion of the handle and has a locking end and a protrusion. The protrusion is formed on the locking end and engages the notch of the blade. The unlocking lever is pivotally mounted on the handle and has a pushing end and at least one propping block. The propping block protrudes from the unlocking lever and abuts the locking rod. Therefore, the folding knife allows users to release the blade by either directly pressing the locking rod or pushing the pushing end of the unlocking lever.