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US Patent 7915393 Compositions and methods for WT1 specific immunotherapy

Patent 7915393 was granted and assigned to Corixa on March, 2011 by the United States Patent and Trademark Office.

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Patent abstract

Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 polynucleotide, a WT1 polypeptide, an antigen-presenting cell presenting a WT1 polypeptide, an antibody that specifically binds to a WT1 polypeptide; or a T cell that specifically reacts with a WT1 polypeptide. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases.

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