Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kun-Hsien Lin0
Ya-Jen Chang0
Alice Yu0
Chi-Huey Wong0
Jung-Tung Hung0
Date of Patent
April 19, 2011
0Patent Application Number
122180820
Date Filed
July 11, 2008
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present disclosure relates to synthetic alpha-galactosyl ceramide (α-GalCer) analogs, and their use as immunotherapies. In one aspect. a method of activating a cytokine response in a subject includes administering an effective amount of a compound to a subject, wherein the subject has an adaptive immune system that includes a population of cells, the population including at least one lymphocyte and at least one antigen-presenting cell, and wherein the compound is represented by the structure of formula 1:
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