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US Patent 7928284 Methods and animal model for analyzing age-related macular degeneration

Patent 7928284 was granted and assigned to University of Kentucky on April, 2011 by the United States Patent and Trademark Office.

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Current Assignee

University of Kentucky

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

April 19, 2011

Patent Application Number

12382702

Date Filed

March 23, 2009

Patent Citations Received

US Patent 11753382 Processes of making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives

US Patent 11913000 Aptamer therapeutics useful in the treatment of complement-related disorders

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US Patent 11992534 Methods for treating and diagnosing blinding eye diseases

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US Patent 12122751 Processes of making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives

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Patent Primary Examiner

Anne-Marie Falk

Patent abstract

Methods for testing candidate drugs for treatment of age-related macular degeneration are provided. Ccl2-deficient, and Ccr2-deficient mice are used to determine the effect of candidate drugs and treatments on development of age-related macular degeneration. Also provided is a Ccl2-deficient, Ccr2-deficient dual knockout mouse, which is a useful animal model for age-related macular degeneration.

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