US Patent 7932213 Small molecule printing
Patent 7932213 was granted and assigned to President and Fellows of Harvard College on April, 2011 by the United States Patent and Trademark Office.
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The present invention provides compositions and methods to facilitate the identification of compounds that are capable of interacting with a biological macromolecule of interest. A composition is provided that comprises an array of chemical compounds attached to a solid support, wherein the density of the array of compounds is at least 1000 spots per cm2. The inventive arrays are generated by: providing a solid support functionalized with a selected chemical moiety capable of interacting with a chemical compound to form an attachment and delivering compounds to the solid support having a density of at least 1000 spots per cm2. The present invention also provides methods for utilizing these arrays to identify small molecule partners for biological macromolecules of interest.
US Patent 07932213 Small molecule printing US Patent 7932213 Small molecule printing
US Patent 07932213 Small molecule printing
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