Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
May 3, 2011
Patent Application Number
10135795
Date Filed
April 30, 2002
Patent Primary Examiner
Patent abstract
The disclosed nucleic acid primer sets, used in combination with quantitative amplification (PCR) of tissue cDNA, can indicate the presence of specific proteases in a tissue sample. Specifically, the present invention relates to expression of hepsin protease. The detected proteases are themselves specifically over-expressed in certain cancers, and the presence of their genetic precursors may serve for early detection of associated ovarian and other malignancies, and for the design of interactive therapies for cancer treatment.
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