Patent attributes
A microfluidic device [10] includes at least one reactant passage [26] and one or more thermal control passages defined therein, the one or more thermal control passages being positioned and arranged within two volumes [12,14] each bordered by a wall [18,20], the walls being generally planar and parallel to one another, the reactant passage positioned between said generally planar walls and defined by said generally planar walls and walls [28] extending between said generally planar walls, wherein the reactant passage comprises multiple successive chambers [34], each such chamber including a split of the reactant passage into at least two sub-passages [36], and a joining [38] of the split passages, and a change of passage direction, of at least one of the sub-passages, of at least 90 degrees.