Is a
Patent attributes
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yulong Hong0
Srikanth Raghavan0
Valerie Lacarriere0
Ye Fang0
Alain R.E. Carre0
Alexander M. Efremov0
Brian L. Webb0
Fang Lai0
...
Date of Patent
May 10, 2011
0Patent Application Number
123306600
Date Filed
December 9, 2008
0Patent Primary Examiner
Patent abstract
The invention relates to G protein-coupled receptor (GPCR) microarrays on porous substrates for structural or functional analyses of GPCRs, and methods of preparing porous substrate surfaces for receiving membranes that comprise GPCRs. In one embodiment, a GPCR microarray of the invention comprises a membrane adhered to an upper surface of a porous substrate, the membrane spanning across a plurality of pores on the porous substrate to form a plurality of cavities having sufficient geometry to permit entry of assay reagents into each cavity, thereby allowing access of assay reagents to both sides of GPCR in the membrane.
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