Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
David B. Passmore0
Mohan Srinivasan0
Alan J. Korman0
Changyu Wang0
Haibin Chen0
Haichun Huang0
Mark J. Selby0
Date of Patent
May 17, 2011
0Patent Application Number
119177270
Date Filed
June 30, 2006
0Patent Citations Received
...
Patent Primary Examiner
Patent abstract
The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies that specifically bind to PD-L1 with high affinity. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. The disclosure also provides methods for detecting PD-L1, as well as methods for treating various diseases, including cancer and infectious diseases, using anti-PD-L1 antibodies.
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