Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Tsukasa Nishihara0
Tomoyuki Koshi0
Toshihiro Nakashima0
Toshiyuki Edano0
Atsuko Sakata0
Masao Ohkuchi0
Sumiyo Takemoto0
Takumi Sasaki0
Date of Patent
May 24, 2011
0Patent Application Number
126449520
Date Filed
December 22, 2009
0Patent Primary Examiner
Patent abstract
A modified Staphylococcal enterotoxin B (SEB) having resistance to a protease and a reduced toxicity and a vaccine comprising said modified SEB are provided. A modified SEB which has an amino acid sequence as set forth in SEQ ID NO: 1 wherein each of the lysine at 97-position and the lysine at 98-position are substituted with any other amino acid, or a derivative thereof and a vaccine comprising said modified SEB or a derivative thereof.
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