Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Neil Aronin0
Phillip D. Zamore0
Date of Patent
May 24, 2011
0Patent Application Number
105717050
Date Filed
September 13, 2004
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to the discovery of an effective treatment for a variety of gain-of-function diseases, in particular, Huntington's disease (HD). The present invention utilizes RNA Interference technology (RNAi) against polymorphic regions in the genes encoding various gain-of-function mutant proteins resulting in an effective treatment for the gain-of-function disease.
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