Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael Kaplitt0
Matthew During0
Date of Patent
June 7, 2011
0Patent Application Number
126853850
Date Filed
January 11, 2010
0Patent Primary Examiner
Patent abstract
The invention provide methods and compositions for localized delivery of a vector comprising a therapeutic agent to a specific region of the brain that is overstimulated in neurodegenerative diseases. In particular, the invention provides methods and compositions used to deliver an adeno-associated virus vector (AAV) comprising a nucleotide sequence encoding glutamic acid decarboxylase (GAD) to cells in the hippocampus, subthalamic nucleus of the basal ganglia, mesaphilia and thalamus.
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