Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jonathan Baell0
Guillaume Laurent Lessene0
Date of Patent
June 7, 2011
0Patent Application Number
116425910
Date Filed
December 21, 2006
0Patent Primary Examiner
Patent abstract
Benzoyl urea derivatives that are alpha helical peptides mimetics that mimic BH3-only proteins, compositions containing them, their conjugation to cell-targeting-moieties, and their use in the regulation of cell death are disclosed. The benzoyl urea derivatives are capable of binding to and neutralizing pro-survival Bcl-2 proteins. Use of benzoyl urea derivatives in the treatment and/or prophylaxis of diseases or conditions associated with deregulation of cell death are also described.
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