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US Patent 7972858 Ultra high-throughput opti-nanopore DNA readout platform

Patent 7972858 was granted and assigned to President and Fellows of Harvard College on July, 2011 by the United States Patent and Trademark Office.

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Patent abstract

Described herein are methods for analyzing polymer molecules. These methods are employed for the high throughput readout of DNA and RNA molecules with single molecule sensitivity. The method of the present invention comprises (1) the electrically controlled unzipping of DNA (or RNA) double strands, and (2) the readout of the molecule's identity (or code) using one or more molecule signal detection.

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