Patent 7973136 was granted and assigned to Xencor on July, 2011 by the United States Patent and Trademark Office.
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcgR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.