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US Patent 7973182 Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols

Patent 7973182 was granted and assigned to Lonza Group on July, 2011 by the United States Patent and Trademark Office.

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Patent abstract

A process for the preparation of enantiomerically pure 1-substituted-3-amino-alcohols, particularly of (S)-(−)- and (R)-(+)-3-N-methylamino-1-(2-thienyl)-1-propanol, by asymmetrically hydrogenating salts of a carboxylic acids with an aminoketone of the formula:

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