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US Patent 7977461 Anti-platelet membrane glycoprotein VI monoclonal antibody

Patent 7977461 was granted and assigned to Mochida Pharmaceutical on July, 2011 by the United States Patent and Trademark Office.

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Patent abstract

The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof:a) It specifically binds to human platelet membrane glycoprotein VI (GPVI);b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; andc) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.

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