Patent 7981999 was granted and assigned to Aileron Therapeutics on July, 2011 by the United States Patent and Trademark Office.
The present invention provides novel peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production. In various embodiments, the peptidomimetic macrocycles are of Formula I: