A chemical genus of purinones and 1H-imidazopyridinones, which are useful as PKCθ. inhibitors, and their methods of use are disclosed. The genus is represented by the formula I:
US Patent 07989459 Purinones and 1H-imidazopyridinones as PKC-theta inhibitorsUS Patent 7989459 Purinones and 1H-imidazopyridinones as PKC-theta inhibitors