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US Patent 7989601 Heterobifunctional pan-selectin inhibitors

Patent 7989601 was granted and assigned to GlycoMimetics on August, 2011 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
GlycoMimetics
GlycoMimetics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
79896010
Patent Inventor Names
Sergei A. Svarovsky0
Beat Ernst0
John L. Magnani0
John T. Patton, Jr.0
Arun K. Sarkar0
Date of Patent
August 2, 2011
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Patent Application Number
127640270
Date Filed
April 20, 2010
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Patent Citations Received
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US Patent 11987598 E-selectin antagonist compounds, compositions, and methods of use
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US Patent 11707474 Methods for treating acute myeloid leukemia and related conditions
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US Patent 11712446 Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
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US Patent 11780873 Highly potent multimeric e-selectin antagonists
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US Patent 11878026 Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
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Patent Primary Examiner
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Shaojia Anna Jiang
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Patent abstract

Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise particular glycomimetics alone or linked to a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids) or a member of a class of compounds termed BACAs (Benzyl Amino Carboxylic Acids).

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