Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
August 9, 2011
Patent Application Number
10586287
Date Filed
January 14, 2005
Patent Primary Examiner
Patent abstract
The present invention relates to metallocene-based phosphine ligands having chirality at phosphorus and at least one other element of chirality (planar chirality and/or chirality at carbon); and to the use of such ligands in asymmetric transformation reactions to generate high enantiomeric excesses of formed compounds. A method for the preparation of ligands according to the invention involving the conversion of the ortho-lithiated substituted metallocene to a phosphine chiral at phosphorus is also disclosed.
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