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US Patent 7998978 Substituted 2-amino-fused heterocyclic compounds

Patent 7998978 was granted and assigned to Pfizer Limited on August, 2011 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein: R1, R2, Z1, t, and ring A are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of JNK, such as diabetes, the method comprising administering to a mammal an effective amount of a compound of formula (I).

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