Patent 7999004 was granted and assigned to National Taiwan University on August, 2011 by the United States Patent and Trademark Office.
The present invention provides compounds having estrogenic activity selected from the group consisting of RRR-α-tocopherol, hydro-Q9 chromene, coenzyme Q9, cycloartane, 1-Feruloyl glycerol, γ-tocopherol-9, and analogues thereof. The compounds of the present invention activate ERα and ERβ, and express high estrogenic activity.