Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
August 16, 2011
Patent Application Number
12638871
Date Filed
December 15, 2009
Patent Primary Examiner
Patent abstract
The present invention is directed to novel methods for in vitro and in vivo detection of target nucleic acid molecules, including DNA and RNA targets, as well as nucleic acid analogues. The present invention is based on protein complementation, in which two individual polypeptides are inactive. When the two inactive polypeptide fragment are brought in close proximity during hybridization to a target nucleic acid, they re-associate into an active, detectable protein.
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