US Patent 8003613 Methods and compositions for inducing apoptosis
Patent 8003613 was granted and assigned to University of Florida on August, 2011 by the United States Patent and Trademark Office.
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Patent abstract
The C-terminal domain of focal adhesion kinase (FAK-CD) was isolated using a Baculoviral system. Using phage display techniques, a phage encoding a 12 amino-acid peptide (peptide 35) and AV3 that binds to FAK-CD were identified. The peptides were also conjugated to TAT-FITC to produce a fluorescently labeled chimeric molecule capable of penetrating cell membranes. Contacting various breast cancer cell lines with these molecule caused detachment, rounding, apoptosis and cell death. These effects were not observed in normal (non-cancerous) breast cells.
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US Patent 08003613 Methods and compositions for inducing apoptosis US Patent 8003613 Methods and compositions for inducing apoptosis
Infobox
Patent Number
0800361300
Patent Number
800361300
Edits on 3 Apr, 2023
Golden AI
Infobox
Is a
Current Assignee
Patent Jurisdiction
Patent Number
080036130
Date of Patent
August 23, 2011
0Patent Application Number
105795290
Date Filed
November 17, 2004
0Patent Primary Examiner
Edits on 27 Sep, 2022
Golden AI
Infobox
Is a
Current Assignee
Patent Jurisdiction
Patent Number
080036130
Date of Patent
August 23, 2011
0Patent Application Number
105795290
Date Filed
November 17, 2004
0Patent Primary Examiner
Edits on 8 Dec, 2021
Golden AI
Edits made to:
Infobox (+8 properties)
US Patent 08003613 Methods and compositions for inducing apoptosis
Infobox
Is a
Current assignee
Patent jurisdiction
Patent number
08003613
Date of patent
August 23, 2011
Patent application number
10579529
Date Filed
November 17, 2004
Patent primary examiner
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