Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yan Chen0
Kim J. Stutzman-Engwall0
Seran Kim0
Sun Ai Raillard0
Anke Krebber0
Claes Gustafsson0
Jeremy S. Minshull0
Date of Patent
August 30, 2011
0Patent Application Number
121079490
Date Filed
April 23, 2008
0Patent Primary Examiner
Patent abstract
The present invention relates to polynucleotide molecules comprising nucleotide sequences encoding an aveC gene product, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures of S. avermitilis. The present invention further relates to vectors, host cells, and mutant strains of S. avermitilis in which the aveC gene has been inactivated, or mutated so as to change the ratio or amount of class 2:1 avermectins produced.
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