Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Francois Mach0
Marie Kosco-Vilbois0
Nicolas Fischer0
Date of Patent
September 6, 2011
0Patent Application Number
122214850
Date Filed
August 4, 2008
0Patent Primary Examiner
Patent abstract
The invention relates to fully human monoclonal antibodies, and fragments thereof, that bind to the chemokine Regulated upon Activation, Normal T-cell Expressed, and Secreted (RANTES, CCL5), thereby modulating the interaction between RANTES and one of more of its receptors, such as, e.g., CCR1, CCR3, CCR4 and CCR5, and/or modulating the biological activities of RANTES. The invention also relates to the use of these or any anti-RANTES antibodies in the prevention or treatment of immune-related disorders and in the amelioration of one or more symptoms associated with an immune-related disorder.
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